Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
New scaffolds identified by cyclization. IC50 values were calculated from duplicate experiments by the least-squares method, and GI50 values were calculated from quadruplicate experiments along with 95% confidence intervals (95% CI) in parentheses. The assay details are shown in the Supporting Information.
