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Degradation effects of PROTAC 6c on ERRα, ERRβ, and ERRγ proteins in MDA-MB-231 cells by Western blot analysis. (A) PROTAC 6c dose-dependently degrades ERRα protein. (B) PROTAC 6c has no effect on the levels of ERRβ and ERRγ protein at indicated concentration. (C) Time-points degradation analysis of PROTAC 6c at 30 nM.
