Reagents and conditions: (a)
1-[bis(dimethylamino)methylene]-1H-1,2,3-triazolo
[4,5-b]-pyridinium 3-oxide hexafluorophosphate (HATU), N,N-diisopropylethylamine (DIPEA), N,N-dimethylformamide (DMF), room temperature (rt), 39–71%;
(b) trifluoroacetic acid (TFA), dichloromethane (DCM), rt.