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. 2019 Mar 11;10(5):780–785. doi: 10.1021/acsmedchemlett.9b00027

Figure 4.

Figure 4

GSK8612 inhibits secretion of IFNβ from THP-1 cells. GSK8612 inhibits secretion of IFNβ (pg/mL) in THP-1 cells stimulated with (A) dsDNA-containing virus (Baculovirus) with a pIC50 = 5.9 (n = 3) or (B) 60 μg/mL cGAMP with a pIC50 = 6.3 (n = 3).