Table 1.
Basic demographic and clinical characteristics of RA patients and RA subgroups.
| Healthy donors N = 10 |
RA patients without infections N = 17 |
RA patients with infections N = 6 |
p value | |
|---|---|---|---|---|
| Gender | ||||
| Male/female | 1/9 | 4/13 | 0/6 | 0.54 |
| Ethnicity, n (%) | ||||
| White/Caucasian | 6 | 13 (76.5) | 3 (50) | |
| Non-white | 4 | 4 (23.5) | 3 (50) | 0.33 |
| Age in years | ||||
| Median (IQR) | 41 (26) | 54 (15) | 55.5 (9) | 0.09 |
| Disease duration in years | ||||
| Median (IQR) | 5 (6) | 10.5 (11) | 0.32 | |
| Age of onset | ||||
| Median (IQR) | 39 (25) | 41.5 (20) | 0.97 | |
| Autoantibody status | ||||
| Seropositive/seronegative RA | 14/3 | 4/2 | 0.57 | |
| Disease activity (CDAI score) | ||||
| Median (IQR) [range] | 2.95 (10.2) [0-37] | 8.5 (4.0) [0-22] | 0.34 | |
| Number of patients | 16 | 5 | ||
| RA medication category | ||||
| MTX-treated/no DMARD | 10/7 | 4/2 | 1.0 | |
| Methotrexate dose (mg/week) | ||||
| Median (IQR) | 17.5 (10) | 22.5 (2.5) | 0.30 | |
| Number of patients | 9 | 3 |
Abbreviations: RA = rheumatoid arthritis; IQR = interquartile range; CDAI score = Clinical Disease Activity Index score.