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. 2019 Apr 29;8(9):e010917. doi: 10.1161/JAHA.118.010917

Figure 11.

Figure 11

Vasodilatory response of mesenteric arteries from wild‐type (WT), Rgs2−/−, and Rgs5−/− mice to acetylcholine (ACh) at nonpregnant (NP), gestation day 15 (D15), and postpartum day 3 (PPD3). All vessels were preconstricted with 10 μmol/L of phenylephrine before the application of increasing concentrations of ACh. A through C, Vasodilatory responses of WT, Rgs2−/−, and Rgs5−/− uterine arteries to ACh at NP (A), D15 (B), and PPD3 (C) period (WT n=6, Rgs2−/− n=6, and Rgs5−/− n=6 mice). Values are expressed as mean±SE of percent increases in vessel lumen diameter. *P<0.05 Rgs5−/− vs Rgs2−/−; #,## P<0.05, 0.01 WT vs Rgs5−/− NP vs D15.