Table 1.
Morphometric Data of Pressurized Uterine Arteries From Rgs2−/−, Rgs5−/−, and WT Mice at 60 mm Hg in Physiological Saline Solution
| Genotype | WT | Rgs2−/− | Rgs5−/− | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Pregnancy day | NP | D15 | PPD3 | NP | D15 | PPD3 | NP | D15 | PPD3 |
| No. of animals | 6 | 6 | 9 | 8 | 6 | 6 | 4 | 6 | 6 |
| Average wall thickness, μm | 18.8±2.6 | 20.2±4.8 | 27.7±1.9 | 19.5±1.6 | 29.2±5.1 | 27.0±1.8 | 26.1±4.9 | 25.1±4.3 | 31.5±3.9 |
| Lumen diameter, μm | 193±9 | 254±22* | 289±16** | 197±6 | 277±15* | 242±27 | 211±11 | 252± 21 | 281±23 |
| Cross‐sectional area, ×1000 μm2 | 12.5±1.8 | 17.5±5.3 | 27.8±2.7* | 13.3±1.1 | 27.7±4.9** | 23.1±3.1 | 19.9± 4.4 | 22.8±5.2 | 30.7± 4.1 |
| Media/lumen ratio | 0.20±0.03 | 0.17±0.04 | 0.19±0.01 | 0.20±0.02 | 0.22±0.04 | 0.23±0.02 | 0.25±0.04 | 0.20±0.03 | 0.24±0.05 |
Values are mean±SE. D15 indicates gestation day 15; NP, nonpregnant; PPD3, postpartum day 3; WT, wild type.
*,**P<0.05, 0.01, NP vs D15 or PPD3.