Table 1.
Basic Characteristics of the Population With MFS
| Variables | Total |
|---|---|
| Sex, men/women | 50:53 |
| Age, y | 38.2±14.9 |
| Height, cm | 179.2±11.2 |
| Weight, kg | 71.1±16.9 |
| Body mass index, kg/m2 | 22.0±4.1 |
| Body surface area, m² | 1.88±0.26 |
| Ghent diagnostic criteria | |
| Total score | 9.7±2.8 |
| Cardiovascular criterion | 81.6 |
| Ocular criterion | 50.5 |
| Family history | 72.8 |
| Fibrillin‐1 mutation | 72.8 |
| Systemic score ≥7 | 88.3 |
| General MFS features | |
| Replacement of the ascending aorta | 36.9 |
| Aortic valve spearing (David) | 27.2 |
| Aortic valve replacement (Bentall) | 9.7 |
| Wrist and thumb sign | 73.8 |
| Severe pectus excavatum | 28.2 |
| Pectus carinatum | 28.2 |
| Hind foot deformity | 1.0 |
| Pes planus | 66.0 |
| Spontaneous pneumothorax | 2.9 |
| Dural ectasia | 52.4 |
| Span ratio >1.05 | 69.9 |
| Scoliosis >20° | 69.9 |
| Reduced extension of elbows | 8.7 |
| Facial features | 63.1 |
| Myopia >3 diopters | 54.4 |
| Skin striae | 81.6 |
| Mitral valve prolapse | 83.5 |
| Treatment | |
| None | 22.3 |
| RAS antagonist | 71.8 |
| β Blocker | 45.6 |
Data are presented as mean±SD, or percentage. MFS indicates Marfan syndrome; RAS, renin‐angiotensin system.