Table 2.
Median values and distribution parameters for the statistically significant discriminators between primary central nervous system lymphoma (PCNSL) and neurosarcoidosis (NS) at various spatial scale filters (SSF) values.
| Parameter | Median value PCNSL | Median value NS | P value |
|---|---|---|---|
| SSF = 0 | |||
| Entropy_ADC | 4.8 | 4.2 | 0.017 |
| Mean-T2 | 449 | 677 | 0.030 |
| Entropy-T2 | 5.6 | 5.1 | 0.017 |
| MPP-T2 | 449 | 677 | 0.030 |
| SSF = 2 | |||
| Mean-T1PC | 148.6 | 249.3 | 0.030 |
| Entropy-TIPC | 6.1 | 5.8 | 0.009 |
| Entropy-ADC | 4.9 | 4.4 | 0.017 |
| Entropy-T2 | 6.2 | 5.7 | 0.004 |
| SSF = 3 | |||
| Entropy-T1PC | 6.2 | 5.8 | 0.030 |
| MPP-T1PC | 522.7 | 646.9 | 0.030 |
| Entropy-ADC | 4.9 | 4.3 | 0.017 |
| Entropy-T2 | 6.3 | 5.7 | 0.004 |
| Kurtosis-DWI | 1.2 | –0.2 | 0.030 |
| SSF = 4 | |||
| Entropy-ADC | 4.9 | 4.3 | 0.017 |
| Entropy-T2 | 6.4 | 5.6 | 0.004 |
| Skewness-T1 | 0.5 | –0.6 | 0.017 |
| Kurtosis-DWI | 0.6 | –0.5 | 0.017 |
| SSF = 5 | |||
| Entropy-T1PC | 6.2 | 5.8 | 0.030 |
| Entropy-ADC | 4.9 | 4.3 | 0.017 |
| Entropy-T2 | 6.3 | 5.6 | 0.004 |
| Skewness-T1 | 0.7 | –0.6 | 0.030 |
| MPP-DWI | 49.1 | 31.2 | 0.017 |
| Skewness-DWI | 0.9 | –0.5 | 0.004 |
| Kurtosis-DWI | 0.1 | –0.7 | 0.009 |
| SSF = 6 | |||
| Entropy-T1PC | 6.2 | 5.8 | 0.017 |
| Entropy-ADC | 4.9 | 4.3 | 0.017 |
| Entropy-T2 | 6.3 | 5.7 | 0.004 |
| Mean-DWI | 61 | –17.1 | 0.030 |
| MPP-DWI | 79.7 | 37.8 | 0.017 |
| Kurtosis-DWI | –0.1 | –0.9 | 0.030 |
ADC: apparent diffusion coefficient; MPP: mean positive pixels; TIPC: T1 post-contrast image; DWI: diffusion weighted imaging; SSF: spatial scale filters.