Table 2.
Complex I, II, and III with identified glutathionylated Cys residues.
| Name | Subunit | Role | Glutathionylated Cys | Note |
|---|---|---|---|---|
| Complex I | NDUFS1 | Core | C75, C367, C463 (S463), C554, C727 | catalytic core |
| NDUFS2 | Core | C347 | catalytic core with UQ site | |
| NDUFB9 | Supernumerary | C4, C31 | Interface with complex III | |
| NDUFA10 | Supernumerary | C183 | At N-terminus of α-helix | |
| NDUFA5 | Supernumerary | C17 | In an exposed loop | |
| NDUFA9 | Supernumerary | C86 | Close to NADPH | |
| NDUFS6 | Supernumerary | C79 (C87) | Close to Cys 115 | |
| NDUFA7 | Supernumerary | C55 | At N-terminus of α-helix | |
| NDUFAB1 | Supernumerary | C140 | Exposed | |
| Complex II | SDHA | C467, C475, C654 | FAD-binding site | |
| Complex III | UQCRC1 | Core | C268, C410, C453 | Close to complex I |
All numbers of Cys residues are based on mouse complex I. If the number is not conserved between mouse and bovine complex I, it is also shown with bovine numbers in parenthesis.