Table 1.

Biochemical analyses in transduced chondrocytes. Values are given as mean (S.D.). DNA contents and proteoglycan production are in μg/10⁴ cells and type‐II collagen production in ng/10⁴ cells

	Days	Normal		OA
		rAAV‐lacZ	rAAV‐hFGF‐2	rAAV‐lacZ	rAAV‐hFGF‐2
Cells (104/sphere)	1	0.77 (0.02)	1.23 (0.02)*	0.66 (0.02)	1.11 (0.01)*
	26	0.35 (0.03)	2.16 (0.01)*	0.31 (0.02)	1.83 (0.02)*
DNA contents	1	0.41 (0.02)	0.82 (0.01)*	0.38 (0.01)	0.75 (0.01)*
	26	0.25 (0.01)	1.57 (0.02)*	0.23 (0.01)	1.46 (0.02)*
Proteoglycan production	1	4.41 (0.01)	4.44 (0.03)	4.09 (0.01)	4.10 (0.04)
	26	4.19 (0.02)	4.21 (0.03)	4.00 (0.02)	4.01 (0.03)
Type‐II collagen production	1	0.14 (0.01)	0.15 (0.01)	0.08 (0.01)	0.09 (0.01)
	26	0.10 (0.01)	0.10 (0.01)	0.06 (0.01)	0.06 (0.01)

*Significant compared with rAAV‐lacZ.