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. 2008 Sep 4;13(8b):2634–2644. doi: 10.1111/j.1582-4934.2008.00490.x

Figure 7.

Figure 7

In primary cells from human OA cartilage FAK interacts with ADAM15 that is not expressed in normal human chondrocytes. (A) Cell lysates (50 μg) of normal (lane a) and OA chondrocytes from 2 different donors (lanes b, c) were applied to SDS/PAGE and immunodetected using anti‐ADAM15 and anti‐FAK antibodies. Actin served as a loading control. (B) Left panel, FAK could be co‐immunoprecipitated from pooled lysates of OA‐chondrocytes using anti‐ADAM15 antibodies, right panel, ADAM15 co‐precipitates specifically with FAK. As control isotype specific IgG were used.