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. 2008 Oct 23;13(8b):2122–2130. doi: 10.1111/j.1582-4934.2008.00561.x

Figure 1.

Figure 1

EGb® 761 has anti‐angiogenic properties in vitro and in vivo. EGb® 761 inhibits proliferation (A), migration (B), tube formation (C) and angiogenesis in the CAM assay (D). (A) HMECs were stimulated with different concentrations of EGb® 761 for 72 hrs. (B) A confluent HUVEC monolayer was scratched and exposed to ECGM, starvation medium (M199) or ECGM containing EGb® 761 for 16 hrs. (C) HMECs were seeded on Matrigel® and were either left untreated (control) or treated with EGb® 761 for 16 hrs. (D) Fertilised eggs were stimulated with FGF (1 ng/dish) alone or FGF and EGb® 761. The dotted circles indicate the position of the dish carrying the growth factor and EGb® 761.