Skip to main content
. 2008 Jul 9;13(8b):2083–2108. doi: 10.1111/j.1582-4934.2008.00415.x

Figure 3.

Figure 3

Inflammatory cells infiltrate the areas of FGF2‐induced neovascularization in Matrigel plugs. Matrigel pellets containing PBS or 150 ng of FGF2 were implanted subcutaneously in mice and examined at day 7 by haematoxylin and eosin staining and immunofluorescence analysis with antibodies specific to the indicated antigens. Note the presence in the implanted FGF2‐Matrigel plugs of numerous CD31+ endothelial cells and of CD45+ infiltrating leucocytes, mainly consisting of CD11b+ monocytes and F4/80+ macrophages. Only scarce Gr‐1+ neutrophils, CD8+ and CD4+ T‐lymphocytes and no CD19+ B‐lymphocytes, NK1.1+ natural killer or CD11c+ dendritic cells are instead detectable. Nuclei are shown by DAPI counterstaining. Original magnification: a–j, ×200; k–o, ×100.