Table 3.
Odds ratios (ORs) and 95% confidence intervals (CIs) for hypertension in relation to reticulocyte levels
| Reticulocytes | p-value | 1 SD increment in reticulocytes | |||
|---|---|---|---|---|---|
| T1 (Low) | T2 | T3 (High) | |||
| No. of participants | 696 | 702 | 700 | ||
| No. of cases (%) | 406 (58.3) | 457 (65.1) | 485 (69.3) | ||
| Model 1 | 1 | 1.46 (1.16, 1.82) | 1.88 (1.49, 2.36) | <0.001 | 1.34 (1.21, 1.47) |
| Model 2 | 1 | 1.36 (1.08, 1.71) | 1.58 (1.24, 2.00) | <0.001 | 1.24 (1.12, 1.38) |
| Model 3 | 1 | 1.20 (0.95, 1.51) | 1.25 (0.97, 1.60) | 0.080 | 1.12 (1.01, 1.25) |
Notes: Model 1: Adjusted for sex and age only. Model 2: Adjusted further for HDL-C, TG, HbA1c, γ-GTP, WBC, and GFR. Model 3: Further adjustment for BMI. Increments in reticulocytes of 1 SD are 5.5×104 cells/μL for men and 5.0×104 cells/μL for women. Hypertension is defined as systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg and/or use of antihypertensive medication.
Abbreviations: HDL-C, HDL-cholesterol; TG, triglyceride; HbA1c, hemoglobin; γ-GTP, γ-glutamyltranspeptidase; WBC, white blood cells; GFR, glomerular filtration rate; BMI, body mass index.