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. 2019 Feb 22;11(3):606–620. doi: 10.1080/19420862.2019.1578147

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© 2019 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 7. — Comparison of Tier 1 biological quality attributes of HLX01, CN-rituximab and EU-rituximab. The dot plots of (a) CD20 binding affinity, (b) FcRn binding affinity and (c) CDC activity were plotted above corresponding equivalence test results showing 90% CI. Each marker shows the activity value of a specific batch: the blue dots show the values of CN-rituximab, red triangles show the values of HLX01, and black squares show the values of EU-rituximab.