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. Author manuscript; available in PMC: 2019 Aug 31.
Published in final edited form as: Clin Sci (Lond). 2018 Aug 30;132(16):1779–1796. doi: 10.1042/CS20180060

Figure 1. AC6−/− mice present lower urinary pH.

Figure 1

(A) Semiquantitative immunoblotting of AC6 protein in 17000 g membrane fraction of whole kidney lysates from AC6−/− and WT mice under baseline conditions. In WT mice, AC6 protein was detected as a smear centered at 150 kDa. No signal was detectable in AC6−/− mice. (B) Summary data of immunoblot in (A) (n=6/genotype). (C) AC6−/− mice presented lower urinary pH but no difference in ammonia or ammonia/creatinine ratios. Urine pH measurements were performed on urine samples from a previously published animal cohort [26]. Values indicate mean ± S.E.M. Abbreviation: ND, not detectable. *P<0.05. Values on bars indicate sample size.