Study	Reason for exclusion
Alberto 1968	Not a head‐to‐head trial of antibiotics. Comparison of mucolytic acetylcysteine vs nothing against background antibiotic therapy
Allen 1988	Not a head‐to‐head trial of antibiotics. Comparison of probenecid, a uricosuric agent, vs nothing against background therapy
Begg 2000	Not restricted exclusively to patients with bronchiectasis. We endeavoured to contact the study authors to ascertain availability of data from bronchiectasis participants, but at the time of publication of this review, the data were unavailable.
Bevilacqua 1973	Not a head‐to‐head trial of antibiotics. Different tetracycline doses
Bilton 2006	Not a head‐to‐head trial of antibiotics. Comparison of dual antibiotic vs single antibiotic alone (included in separate review of dual antibiotics)
Bradley 2011	Intervention was not an antibiotic.
Brambilla 1992	Not restricted exclusively to patients with bronchiectasis, and no separate subgroup analysis for patients with bronchiectasis. We endeavoured to contact the study authors to ascertain availability of data from bronchiectasis participants, but at the time of publication of this review, the data were unavailable.
Cherniack 1959	Not a randomised controlled trial
Finegold 1981	Not restricted exclusively to patients with bronchiectasis. Although distribution of initial diagnosis and treatment response was provided in Table 2, study authors provided no data on the total number of patients with bronchiectasis in each group. We were unable to contact the study authors for further information.
Garcia‐Rodriguez 1984	Not restricted exclusively to patients with bronchiectasis. We were unable to contact the study authors for further information.
Ip 1998	Not a head‐to‐head trial of antibiotics. Same antibiotic was administered by different delivery methods.
Jia 2010	Not restricted exclusively to patients with bronchiectasis, and no separate subgroup analysis for patients with bronchiectasis. We endeavoured to contact the study authors to ascertain availability of data from bronchiectasis participants, but at the time of publication of this review, the data were unavailable.
Khan 2003	Does not include bronchiectasis patients
Kobayashi 1984	Not restricted exclusively to patients with bronchiectasis. We were unable to contact the study authors for further information.
Kobbernagel 2016	Does not include bronchiectasis patients
Krawczyk 1981	Does not include bronchiectasis patients
Lioberes 1990	Not a randomised controlled trial
Liu 2012	Not a head‐to‐head trial of antibiotics. Single antibiotic vs control
Mehta 1991	Not a randomised controlled trial
Nakamura 2007	Not restricted exclusively to patients with bronchiectasis. We endeavoured to contact the study authors to ascertain availability of data from bronchiectasis participants, but at the time of publication of this review, the data were unavailable.
NCT03058718	Not a head‐to‐head trial. Procalcitonin‐guided antibiotic therapy
NCT03093974	Not a head‐to‐head trial. Single antibiotic vs placebo
Pines 1964	Not restricted exclusively to patients with bronchiectasis. We were unable to contact the study authors for further information.
Pines 1967	Not restricted exclusively to patients with bronchiectasis. We were unable to contact the study authors for further information.
Pines 1981	Not restricted exclusively to patients with bronchiectasis. We were unable to contact the study authors for further information.
Ramer 1981	Not restricted exclusively to patients with bronchiectasis. We were unable to contact the study authors for further information.