Cochrane Library (via Wiley) search strategy

#1. MeSH descriptor: [Erectile Dysfunction] explode all trees #2. Erectile dysfunction* or Erectile function* or Impoten* or Penile erect* or ED:ti,ab,kw (Word variations have been searched) #3. ((sex or sexual*) near/3 (function* or dysfuc* or problem* or symptom* or arous*)):ti,ab,kw (Word variations have been searched) #4. #1 or #2 or #3 #5. MeSH descriptor: [Testosterone] explode all trees #6. "testosterone enanthate" or "testosterone undecanoate" or "testosterone Propionate" or Androgel or Axiron or Fortesta or Testim or Nebido or Andriol:ti,ab,kw (Word variations have been searched) #7. MeSH descriptor: [Androgens] explode all trees #8. Androderm or Testoderm or Methyltestosterone or Natesto or Striant:ti,ab,kw (Word variations have been searched) #9. #5 or #6 or #7 or #8 #10. #4 and #9

MEDLINE (Ovid) search strategy

#1. exp Erectile Dysfunction/ #2. Erectile dysfunction$.tw. #3. Erectile function$.tw. #4. Impoten$.tw. #5. Penile erect$.tw. #6. ED.tw. #7. ((sex or sexual$) adj3 (function$ or dysfuc$ or problem$ or symptom$ or arous$)).tw. #8. 1 or 2 or 3 or 4 or 5 or 6 or 7 #9. exp Testosterone/ #10. testosterone enanthate.tw. #11. testosterone undecanoate.tw. #12. testosterone Propionate.tw. #13. Androgel.tw. #14. Axiron.tw. #15. Fortesta.tw. #16. Testim.tw. #17. Nebido.tw. #18. Andriol.tw. #19. exp Androgens/ #20. Androderm.tw. #21. Testoderm.tw. #22. Methyltestosterone.tw. #23. Natesto.tw. #24. Striant.tw. #25. 9 ‐24 OR #26. 8 and 25 #27. randomized controlled trial.pt. #28. controlled clinical trial.pt. #29. randomized.ab. #30. placebo.ab. #31. drug therapy.fs. #32. randomly.ab. #33. trial.ab. #34. groups.ab. #35. 27 ‐ 34 OR #36. exp animals/ not humans.sh. #37. 30 not 31 #38. 26 and 37

Embase (via Elsevier) search strategy

#1. 'erectile dysfunction'/exp #2. 'Erectile dysfunction*':ab,ti #3. 'Erectile function*':ab,ti #4. Impoten*:ab,ti #5. 'Penile erect*':ab,ti #6. ED:ab,ti #7. ((sex or sexual*) NEAR/3 (function* or dysfuc* or problem* or symptom* or arous*)):ab,ti #8. #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 #9. 'testosterone'/exp #10. 'testosterone enanthate':ab,ti #11. 'testosterone undecanoate':ab,ti #12. 'testosterone Propionate':ab,ti #13. Androgel:ab,ti #14. Axiron:ab,ti #15. Fortesta:ab,ti #16. Testim:ab,ti #17. Nebido:ab,ti #18. Andriol:ab,ti #19. 'androgen'/exp #20.. Androderm:ab,ti #21. Testoderm:ab,ti #22. Methyltestosterone:ab,ti #23. Natesto:ab,ti #24. Striant:ab,ti #25. #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24 #26. #8 AND #25 #27. crossover procedure':de OR 'double‐blind procedure':de OR 'randomized controlled trial':de OR 'single‐blind procedure':de OR random*:de,ab,ti OR factorial*:de,ab,ti OR crossover*:de,ab,ti OR ((cross NEXT/1 over*):de,ab,ti) OR placebo*:de,ab,ti OR ((doubl* NEAR/1 blind*):de,ab,ti) OR ((singl* NEAR/1 blind*):de,ab,ti) OR assign*:de,ab,ti OR allocat*:de,ab,ti OR volunteer*:de,ab,ti #28. ('animals'/exp) NOT ('humans'/exp and 'animals'/exp) #29. #27 NOT #28 #30. #26 AND #29

LILAC search strategy

#1. (mh:("Erectile Dysfunction")) OR (tw:("erectile dysfunction" OR "erectile function" OR impotence OR "penile erection" OR ED OR "sexual dysfuction" OR "sexual function" OR "sexual problem" OR "sexual symptom" OR "sexual arousal")) #2. (mh:(Testosterone OR Androgens)) OR (tw:(testosterone OR "testosterone enanthate" OR "testosterone undecanoate" OR "testosterone Propionate" OR androgel OR axiron OR fortesta OR testim OR nebido OR andriol OR androgens OR androderm OR testoderm OR methyltestosterone OR natesto OR striant)) #3. 1 AND 2 #4. "((PT:""randomized controlled trial"" OR PT:""controlled clinical trial"" OR PT:""multicenter study"" OR MH:""randomized controlled trials as topic"" OR MH:""controlled clinical trials as topic"" OR MH:""multicenter study as topic"" OR MH:""random allocation"" OR MH:""double‐blind method"" OR MH:""single‐blind method"") OR ((ensaio$ OR ensayo$ OR trial$) AND (azar OR acaso OR placebo OR control$ OR aleat$ OR random$ OR enmascarado$ OR simpleciego OR ((simple$ OR single OR duplo$ OR doble$ OR double$) AND (cego OR ciego OR blind OR mask))) AND clinic$)) AND NOT (MH:animals OR MH:rabbits OR MH:rats OR MH:primates OR MH:dogs OR MH:cats OR MH:swine OR PT:""in vitro"")" #5. 3 AND 4

ClinicalTrials.gov

#1. ("erectile dysfunction" OR "erectile function" OR impotence OR "penile erection" OR ED OR "sexual dysfuction" OR "sexual function" OR "sexual problem" OR "sexual symptom" OR "sexual arousal") #2. (testosterone OR "testosterone enanthate" OR "testosterone undecanoate" OR "testosterone Propionate" OR androgel OR axiron OR fORtesta OR testim OR nebido OR andriol OR androgens OR androderm OR testoderm OR methyltestosterone OR natesto OR striant) #3. 1 AND 2

World Health Organization International Clinical Trials Registry Platform Search Portal

#1. In the title = ("erectile dysfunction" OR "erectile function" OR impotence OR "penile erection" OR ED OR "sexual dysfuction" OR "sexual function" OR "sexual problem" OR "sexual symptom" OR "sexual arousal") AND In the intervention= (testosterone OR "testosterone enanthate" OR "testosterone undecanoate" OR "testosterone Propionate" OR androgel OR axiron OR fORtesta OR testim OR nebido OR andriol OR androgens OR androderm OR testoderm OR methyltestosterone OR natesto OR striant)