Study characteristics	Data to be extracted	Instruction for data extraction
Study ID	(Surname of first author and publication year of first full report of study)
Study information	Study title	Enter the title of the study.
Methods	Randomisation methods	How is the randomisation sequence generated?
	Blinding	Are participants, outcome assessors, or providers blinded to which treatment is given?
	Numbers of recruitment locations	At how many study sites are participants recruited for the trial?
Participants	Inclusion criteria	Enter the characteristics that the participants must have in this trial.
	Exclusion criteria	Enter the characteristics that the participants cannot have if enrolled in this trial.
	Numbers of participants randomised	How many participants were randomised in this trial?
	Mean age (years)	Enter the mean age ± SD of participants assigned to each group.
	Sex (% male)	Enter the percentage of male participants assigned to each group.
	Numbers of participants analysed	Data from how many participants are analysed in this trial?
	Numbers of dropouts	How many randomised participants are lost to follow‐up during the study period?
	Dropout reasons	What are the reasons for participant dropouts?
Interventions	Types of interventions	Enter the types and methods of interventions, for example, topical antibiotics, antiseptic agents, systemic antibiotics, phototherapy, or surgical interventions.
	Names of medications or methods	Enter the names of the interventions, such as the generic name of drugs.
	Dosage	Enter the dose and frequency for drugs. Enter the duration and frequency for phototherapy. For surgical intervention, enter 'N/A'.
	Duration	How long do participants receive therapy?
	Time point	When are the outcomes measured?
Outcomes	Primary outcomes	Enter data on primary outcomes.
	Secondary outcomes	Enter data on secondary outcomes.