Skip to main content
. 2019 May 1;15(5):e1008123. doi: 10.1371/journal.pgen.1008123

Fig 2. Replication of BMD association on Chr. 3@52.5 Mbp in both sexes in multiple independent populations.

Fig 2

A) Bmd40, a QTL impacting BMD in an F2 cross between C57BL/6J and C3H/HeJ, overlaps the Chr. 3 association at 52.5 Mbp. Replication of the Chr. 3 association at 52.5 Mbp in the “Naggert” (N = 31), males (B) and females (C), and “Tordoff” (N = 30), males (D) and females (E), inbred strain panels. Chromosome-wide significance was -logP>2.9 in both strain sets. Non-ref (C3H/HeJ) alleles of associated SNPs increase BMD in the “Ackert” (F), “Tordoff1” (G), and “Naggert1” (H) strain panels and the BXH F2 intercross (I).