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. 2018 Aug 14;2018(8):CD012327. doi: 10.1002/14651858.CD012327.pub2
Summary for the risk of death or serious morbidity composite for infants born to mothers with GDM
No conclusions possible: low‐ to very low‐quality evidence, or insufficient evidence to comment on the effectiveness, more evidence needed
  • Moderate‐quality evidence showed no clear difference for insulin versus oral anti‐diabetic pharmacological therapies.

  • Moderate‐quality evidence showed no clear difference exercise versus control although the direction of the effect suggested benefit favouring exercise.

  • Low‐quality evidence suggested a reduction in the risk of death or serious morbidity composite outcomes for babies born to mothers with GDM who were treated with metformin compared to glibenclamide.

  • Very low‐quality evidence showed an increased risk of a death or serious morbidity composite for twice daily insulin regimen versus four times daily insulin regimen.

  • Very low‐quality evidence showed no clear difference for ethnic specific diet versus standard healthy diet; lifestyle intervention versus usual care or diet alone; or managed by telemedicine versus standard care for glucose monitoring