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CYC116 inhibits secretion of TNF-α and IL-6 from BMMCs. BMMCs were stimulated with 50 ng/ml antigen for 3 h with or without CYC116. The cultured media were subjected to ELISA for TNF-α (A) and IL-6 (B). The values are presented as the mean ± SEM from three independent experiments in triplicate. Significant differences compared to the antigen-only group are indicated, *p<0.05 and **p<0.01. Ag, antigen.
