2008‐002273‐12.

Trial name or title	Long term opioid administration in oncologic chronic pain: open label, prospective study on efficacy, safety and pharmacogenetic factors.
Methods	Randomised, parallel‐group, open controlled trial.
Participants	Inclusion criteria: Age > 18 years. Oncologic, chronic, neuropathic or nociceptive peripheric pain or both. Exclusion criteria: Abuse history. Opioid analgesic use history. Opioid allergies.
Interventions	Morphine (oral solution) Morphine (oral tablet) Oxycodone (oral tablet) Fentanyl (TD patch) Buprenorphine (TD patch) Hydromorphone (prolonged‐release oral tablet)
Outcomes	Pain reduction at least 40% in VAS scale.
Starting date	Not reported.
Contact information	Location: Italy. Sponsors: Ospedale Policlinico S. Matteo. Principal investigators: Not reported.
Notes	Target enrolment: N = 320. Study completion date: Unknown but of 3‐year duration. Other study ID numbers: None reported, but is it the same as NCT00916890 below?