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. 2018 Apr 18;2018(4):CD006545. doi: 10.1002/14651858.CD006545.pub3

NCT00744185.

Methods Parallel‐group, phase II and III, RCT
Participants Up to 4 months of age, male and female, 1 or more haemangiomas sized more than 1 cm in diameter, social insurance, infant not threatened for vital or functional structure and for which no treatment would be proposed
Age: up to 4 months
Sex: all
Country: France
Interventions Propranolol (3 mg/kg for 15 days then 4 mg/kg for 15 days) versus placebo (for 30 days)
Outcomes Primary outcome:
  • Proportion of haemangioma thickness variation, measured using ultrasonography from the basal state after 1 month


Secondary outcomes:
  • Proportion of haemangioma size variation, measured clinically and with photography from the basal state after 1 month

  • Observance

Notes This study has been terminated. (Study halted prematurely due to difficulties in recruitment of participants.)