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. 2018 Aug 10;2018(8):CD012812. doi: 10.1002/14651858.CD012812.pub2

Duerksen 2004.

Methods Design: retrospective case series
Aim: to determine whether a subgroup of participants with intestinal obstruction would benefit from support with PN.
Patients receiving PN at home and in hospital included in study, only HPN patients included in this review.
Country: Canada
Funding: not reported
Participants Number: 5
Inclusion criteria
  • No evidence of end‐organ failure

  • An obstructed GI tract

  • An estimated life expectancy longer than 2 to 3 months


Exclusion criteria: not reported
Age: mean 44.6 years (37 to 57)
Gender: 2 female and 3 male
Cancer site: (n)
  • Colon (3)

  • Gastric (2)


Patient in MBO: 100%
Performance status: median Karnofsky performance status 60 (50 to 70)
Treatment received: chemotherapy 3
Interventions HPN given to all participants. No information was given about nutritional support aims or composition of PN solutions.
Outcomes
  • Length of survival: unclear how it was measured

  • Adverse events: unclear how this was measured

Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk No randomisation
Allocation concealment (selection bias) High risk No group allocation concealment
Criteria for assignment to treatments Unclear risk Insufficient information to permit judgement
Comparability of treatment groups Unclear risk Only one treatment group
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No blinding
Blinding of outcome assessment (detection bias) 
 All outcomes High risk No blinding
Incomplete outcome data (attrition bias) 
 All outcomes Low risk
  • Length of survival: no missing data

  • Adverse events: no missing data

Selective reporting (reporting bias) Unclear risk Insufficient information to permit judgement
Other bias Low risk The study appears to be free of other sources of bias