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. 2018 Sep 10;2018(9):CD007287. doi: 10.1002/14651858.CD007287.pub4

Method 2002.

Methods Randomised controlled study
Participants 102 women with ovarian cancer after primary therapy (disease status at study entry not described)
Interventions Intravenous monoclonal antibody (oregovomab ‐ CA‐125): 2 gifts vs 3 gifts vs 6 gifts
Outcomes Tumour responses
Immune response: humoral (Ab2, HAMA), cellular
Adverse events
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Information about the sequence generation process insufficient to permit judgement of ‘low risk’ or ‘high risk’; only abstract available
Allocation concealment (selection bias) Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’; only abstract available
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk No blinding or incomplete blinding, but review authors judge that the outcome is not likely to be influenced by lack of blinding
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’; only abstract available
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Reporting of attrition/exclusions insufficient to permit judgement of ‘low risk’ or ‘high risk'; only abstract available
Selective reporting (reporting bias) Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’; only abstract available
Other bias Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’; only abstract available