Method 2002.
Methods | Randomised controlled study | |
Participants | 102 women with ovarian cancer after primary therapy (disease status at study entry not described) | |
Interventions | Intravenous monoclonal antibody (oregovomab ‐ CA‐125): 2 gifts vs 3 gifts vs 6 gifts | |
Outcomes | Tumour responses Immune response: humoral (Ab2, HAMA), cellular Adverse events |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Information about the sequence generation process insufficient to permit judgement of ‘low risk’ or ‘high risk’; only abstract available |
Allocation concealment (selection bias) | Unclear risk | Information insufficient to permit judgement of ‘low risk’ or ‘high risk’; only abstract available |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | No blinding or incomplete blinding, but review authors judge that the outcome is not likely to be influenced by lack of blinding |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Information insufficient to permit judgement of ‘low risk’ or ‘high risk’; only abstract available |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Reporting of attrition/exclusions insufficient to permit judgement of ‘low risk’ or ‘high risk'; only abstract available |
Selective reporting (reporting bias) | Unclear risk | Information insufficient to permit judgement of ‘low risk’ or ‘high risk’; only abstract available |
Other bias | Unclear risk | Information insufficient to permit judgement of ‘low risk’ or ‘high risk’; only abstract available |