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. 2018 Sep 10;2018(9):CD007287. doi: 10.1002/14651858.CD007287.pub4

Odunsi 2007.

Methods Uncontrolled phase I study
Participants 18 ovarian cancer patients after chemotherapy for primary or recurrent disease with or without residual disease
Interventions Subcutaneous short peptide (NY‐ESO‐1)
Adjuvant: incomplete Freund's adjuvant
Outcomes Survival: median time to progression: 19.0 months
Tumour responses: 1× CR, 17× unknown
Immune responses: humoral, cellular
Adverse events: well tolerated, no further description
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk Uncontrolled trial
Allocation concealment (selection bias) High risk Uncontrolled trial
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’
Selective reporting (reporting bias) Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’
Other bias Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’