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. 2018 Sep 10;2018(9):CD007287. doi: 10.1002/14651858.CD007287.pub4

Rahma 2012.

Methods Uncontrolled phase II study
Participants 21 ovarian cancer patients without evidence of disease after prior therapy
Interventions Subcutaneous short peptide (p53) vs intravenous peptide‐pulsed dendritic cells (p53)
Adjuvant: Montanide ISA‐51 and GM‐CSF (only in cohort treated with peptide)
Outcomes Survival (progression‐free survival, overall survival)
Tumour responses
Immune responses: cellular
Adverse events
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk Uncontrolled trial
Allocation concealment (selection bias) High risk Uncontrolled trial
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’
Selective reporting (reporting bias) Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’
Other bias Unclear risk Information insufficient to permit judgement of ‘low risk’ or ‘high risk’