Sandmaier 1999.
Methods | Uncontrolled phase II study | |
Participants | 40 breast or ovarian cancer (n = 7) patients who underwent high‐dose chemotherapy and autologous or syngeneic stem cell rescue (disease status at study entry unknown) | |
Interventions | Subcutaneous KLH conjugate (Sialyl‐Tn) Adjuvant: Detox B |
|
Outcomes | Immune responses: humoral, cellular | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | High risk | Uncontrolled trial |
Allocation concealment (selection bias) | High risk | Uncontrolled trial |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Information insufficient to permit judgement of ‘low risk’ or ‘high risk’ |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Information insufficient to permit judgement of ‘low risk’ or ‘high risk’ |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Information insufficient to permit judgement of ‘low risk’ or ‘high risk’ |
Selective reporting (reporting bias) | Unclear risk | Information insufficient to permit judgement of ‘low risk’ or ‘high risk’ |
Other bias | Unclear risk | Information insufficient to permit judgement of ‘low risk’ or ‘high risk’ |