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. 2018 Aug 21;2018(8):CD012317. doi: 10.1002/14651858.CD012317.pub2

McDonagh 2012.

Methods RCT, parallel design
Participants Number of randomized participants: 200
Inclusion criteria
  1. ≥ 65 years of age, after obtaining IRB approval and informed consent


Exclusion criteria
  1. Not fluent in English

  2. Severe visual or auditory deficits

  3. Diagnosis of dementia

  4. Score 18 on the MMSE


Type of surgery: orthopaedic
Country: not reported
Setting: hospital
Interventions TIVA group
Induction details: pre‐medicated with midazolam. Induction with propofol; no additional details
Maintenance details: propofol TIVA to maintain BIS 40 to 60
Inhalational maintenance group
Induction details: pre‐medicated with midazolam Induction with propofol; no additional details
Maintenance details: isoflurane to maintain BIS 40 to 60
Outcomes
  1. Cognitive function at 3 months postsurgery using GDS. Cognitive testing using standardized cognitive measures

Notes We only have an abstract for this study. No denominator figures for each group. Not clear whether outcome data is available for immediate postoperative period