McDonagh 2012.

Methods	RCT, parallel design
Participants	Number of randomized participants: 200 Inclusion criteria ≥ 65 years of age, after obtaining IRB approval and informed consent Exclusion criteria Not fluent in English Severe visual or auditory deficits Diagnosis of dementia Score 18 on the MMSE Type of surgery: orthopaedic Country: not reported Setting: hospital
Interventions	TIVA group Induction details: pre‐medicated with midazolam. Induction with propofol; no additional details Maintenance details: propofol TIVA to maintain BIS 40 to 60 Inhalational maintenance group Induction details: pre‐medicated with midazolam Induction with propofol; no additional details Maintenance details: isoflurane to maintain BIS 40 to 60
Outcomes	Cognitive function at 3 months postsurgery using GDS. Cognitive testing using standardized cognitive measures
Notes	We only have an abstract for this study. No denominator figures for each group. Not clear whether outcome data is available for immediate postoperative period