| Trial name or title |
Sevoflurane versus standard general anaesthesia in elective open abdominal aortic aneurism surgery |
| Methods |
RCT, parallel design |
| Participants |
Target number of randomized participants: 24
Inclusion criteria
Enrolled for abdominal infrarenal aortic aneurism repair surgery
Exclusion criteria
< 18 years of age Included in other pharmaceutical studies Abuse of opioids, benzodiazepines, anti‐epileptic drugs, alcohol or alpha 2‐agonists pregnant and breastfeeding women Family history of malignant hyperthermia Known hypersensitivity for opioids, propofol or volatile anaesthetics Serious arrhythmia, ventricular tachycardia or tachycardia > 120 beats/min Severe valvular diseases requiring surgical repair before major noncardiac surgery Uncontrolled hypertension Unstable angina pectoris or MI within 30 days of inclusion Requiring acute abdominal aortic aneurysm surgery, or endovascular abdominal aortic aneurysm surgery Severe uncontrolled psychiatric disease
Type of surgery: aortic aneurysm repair
Country: Denmark
Setting: hospital |
| Interventions |
TIVA group
Details: propofol; no details
Inhalational maintenance group
Details: sevoflurane; no details |
| Outcomes |
Biochemical measurements Need for inotropic support MI Intestinal ischaemia diagnosed with endoscopy, laparoscopy or angiograph during admission Postoperative incidences of ARDS and need for dialysis Need for postoperative respiratory support Days until discharge Days in ICU 30‐day mortality |
| Starting date |
Not clear from the clinical trials register documents |
| Contact information |
Peder Bach (pedebach@rm.dk) |
| Notes |
Study does not specifically recruit elderly participants. Once completed, we would need to ascertain whether mean age of participants is > 60 years of age |
