NCT02133638.
Trial name or title | Sevoflurane decreases the risk of postoperative delirium after cerebral hypoxemia during surgery |
Methods | RCT, parallel design |
Participants |
Target number of randomized participants: 130 Inclusion criteria
Exclusion criteria
Type of surgery: elective non‐cardiac surgery (hemicolectomy, hernioplasty, laparoscopic cholecystectomy and laparoscopic hysterectomy) Country: Russia Setting: hospital |
Interventions |
TIVA group Induction details: propofol 2 mg/kg and fentanyl 4 µg/kg Maintenance details: infusion of propofol 8 mg/kg/hour and boluses of fentanyl 3 µg/kg Inhalational maintenance group Induction details: fentanyl 2 µg/kg and a bolus inhalation of 8% sevoflurane in an 8 L/min fresh gas flow Maintenance details: 1 MAC sevoflurane at a low fresh gas flow of 0.6 to 0.8 L/min in a 60% air‐oxygen mixture supplemented with boluses of fentanyl |
Outcomes |
|
Starting date | May 2014 |
Contact information | Yuri V Iljin, Negovsky Reanimatology Research Institute, Moscow, Russia |
Notes |