1.3. Analysis.
Comparison 1 GABA AGONIST DRUGS versus PLACEBO, Outcome 3 Tardive dyskinesia: 3. Average endpoint scores (different scales, high score = poor, data skewed).
| Tardive dyskinesia: 3. Average endpoint scores (different scales, high score = poor, data skewed) | ||||||
|---|---|---|---|---|---|---|
| Study | Intervention | Mean | SD | N | Scale | Notes |
| Gerlach 1978 | Baclofen | 3.7 | 2.4 | 10 | Gerlach scale | |
| Gerlach 1978 | Placebo | 5.3 | 2.2 | 8 | ||
| Mei 2008 | GABA | 6.02 | 3.03 | 20 | AIMS | suggests a statistically significant effet in favour of GABA |
| Mei 2008 | Placebo | 9.35 | 4.26 | 20 | ||
| Stewart 1982 | Baclofen | 11 | 7.35 | 13 | AIMS | |
| Stewart 1982 | Placebo | 12.35 | 6.79 | 17 | ||
| Yin 2004 | Sodium valproate | 6.05 | 3.01 | 39 | AIMS | suggests a statistically significant effet in favour of sodium valproate |
| Yin 2004 | Placebo | 9.36 | 4.16 | 40 | ||