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. 2018 Aug 31;2018(8):CD012610. doi: 10.1002/14651858.CD012610.pub2

Comparison 1. Lipid‐based nutrient supplements (LNS) versus iron folic acid (IFA).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Gestational weight gain 2 3539 Std. Mean Difference (IV, Random, 95% CI) 0.46 [‐0.44, 1.36]
2 Maternal anaemia 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
3 Maternal mortality 3 5628 Risk Ratio (M‐H, Random, 95% CI) 0.53 [0.12, 2.41]
4 Adverse effects 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
5 Low birth weight (LBW) 3 4826 Risk Ratio (M‐H, Random, 95% CI) 0.87 [0.72, 1.05]
6 Weight at birth 3 5077 Mean Difference (IV, Random, 95% CI) 53.28 [28.22, 78.33]
7 Length at birth 3 4986 Mean Difference (IV, Random, 95% CI) 0.24 [0.11, 0.36]
8 Small‐for‐gestational age (SGA) 3 4823 Risk Ratio (M‐H, Random, 95% CI) 0.94 [0.89, 0.99]
9 Preterm births 3 4924 Risk Ratio (M‐H, Random, 95% CI) 0.94 [0.80, 1.11]
10 Duration of gestation 3 5033 Mean Difference (IV, Random, 95% CI) 0.18 [0.04, 0.32]
11 Miscarriage 2 4714 Risk Ratio (M‐H, Random, 95% CI) 0.87 [0.66, 1.14]
12 Stillbirth 3 5575 Risk Ratio (M‐H, Random, 95% CI) 1.14 [0.52, 2.48]
13 Head circumference 2 4057 Mean Difference (IV, Random, 95% CI) 0.20 [0.20, 0.20]
14 Head circumference z score 3 4982 Std. Mean Difference (IV, Random, 95% CI) 0.11 [0.04, 0.18]
15 Mid‐upper‐arm circumference (MUAC) 2 4374 Mean Difference (IV, Random, 95% CI) 0.12 [‐0.02, 0.26]
16 Newborn stunting 2 4166 Risk Ratio (M‐H, Random, 95% CI) 0.82 [0.71, 0.94]
17 Newborn underweight 2 4174 Risk Ratio (M‐H, Random, 95% CI) 0.84 [0.63, 1.13]
18 Neonatal death 3 7172 Risk Ratio (M‐H, Random, 95% CI) 0.72 [0.47, 1.10]
18.1 Early neonatal 3 5555 Risk Ratio (M‐H, Random, 95% CI) 0.70 [0.45, 1.09]
18.2 Late neonatal 2 1617 Risk Ratio (M‐H, Random, 95% CI) 0.96 [0.14, 6.51]