Comparison 2. SSRI or SNRI versus another active drug (amitriptyline).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Migraine frequency (number of migraine attacks)	2	96	Std. Mean Difference (IV, Random, 95% CI)	0.04 [‐0.72, 0.80]
1.1 SSRI	1	44	Std. Mean Difference (IV, Random, 95% CI)	‐0.36 [‐0.96, 0.24]
1.2 SNRI	1	52	Std. Mean Difference (IV, Random, 95% CI)	0.42 [‐0.13, 0.97]