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. 2015 Apr 1;2015(4):CD002919. doi: 10.1002/14651858.CD002919.pub3
Date Event Description
8 April 2016 Amended Affiliation added for LM.
30 April 2015 Amended Minor spelling inconsistencies corrected.
1 April 2015 Review declared as stable This review will be assessed for further updating in 2020.
24 January 2014 New citation required and conclusions have changed This is an update of the review 'Selective serotonin re‐uptake inhibitors (SSRIs) for preventing migraine and tension‐type headaches'. We have implemented the following major changes:
  • the intervention includes selective serotonin and serotonin‐norepinephrine reuptake inhibitors;

  • the population is adults with episodic and chronic migraine;

  • tension‐type headache is the topic of another Cochrane review;

  • the search strategy has been revised to account for these changes and updated in November 2014.


We included three new studies (253 participants) in this update (Bulut 2004; Ozyalcin 2005; Tarlaci 2009). Overall, we included 11 studies and 585 participants.
We recommend that previous readers of the review should re‐read this update.
14 November 2013 New search has been performed We have updated this review to include the results of a new search and to include a new class of antidepressants (serotonin‐norepinephrine reuptake inhibitors). We have added a study flow chart, 'Risk of bias' tables, and 'Summary of findings' tables.
10 August 2009 Amended Contact details updated.
28 October 2008 Amended Converted to new review format.