Rui 2001.
Methods | Generation of allocation sequence: unclear. Allocation concealment: unclear. Blinding: not performed. Follow‐up: unclear. Sample size: no. |
|
Participants | Inclusion criteria:
‐ biopsy proven NASH
‐ no history of alcohol abuse
‐ adults. Exclusion criteria: not reported. Characteristics of included patients: n = 22 Mean age = 53.1 (SD 7.9) Males = 41% |
|
Interventions | DanNingPian (5 tablets TID for 12 weeks) versus reduced glutathione (TAD) (1200 mg with 0.9 NS 500 ml IV infusion QD for 2 to 3 weeks). | |
Outcomes | Liver function tests assessed at 4 and 12 weeks. Definition of remarkably effective: two or more than two liver function indicators completely back to normal. Definition of effective: two or more than two liver function indicators reduced for more than 50%. Definition of ineffective: no improvement or others. | |
Notes | Also patients with type 2 diabetes/IGT, hyperlipidemia and/or obesity were included in both groups. The majority of them complained of GI symptoms. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |