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. 2007 Jan 24;2007(1):CD004996. doi: 10.1002/14651858.CD004996.pub3

Rui 2001.

Methods Generation of allocation sequence: unclear.
Allocation concealment: unclear.
Blinding: not performed.
Follow‐up: unclear.
Sample size: no.
Participants Inclusion criteria: 
 ‐ biopsy proven NASH 
 ‐ no history of alcohol abuse 
 ‐ adults.
Exclusion criteria: not reported.
Characteristics of included patients: 
 n = 22 
 Mean age = 53.1 (SD 7.9) 
 Males = 41%
Interventions DanNingPian (5 tablets TID for 12 weeks) versus reduced glutathione (TAD) (1200 mg with 0.9 NS 500 ml IV infusion QD for 2 to 3 weeks).
Outcomes Liver function tests assessed at 4 and 12 weeks. 
 Definition of remarkably effective: two or more than two liver function indicators completely back to normal. 
 Definition of effective: two or more than two liver function indicators reduced for more than 50%. 
 Definition of ineffective: no improvement or others.
Notes Also patients with type 2 diabetes/IGT, hyperlipidemia and/or obesity were included in both groups. The majority of them complained of GI symptoms.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear