Comparison 8. Two weeks of AmBd + FLU versus two weeks of AmBd.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Mortality	3		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 2 weeks	3	371	Risk Ratio (M‐H, Random, 95% CI)	0.90 [0.45, 1.77]
1.2 10 weeks	3	371	Risk Ratio (M‐H, Random, 95% CI)	0.94 [0.55, 1.62]
1.3 6 months	1	198	Risk Ratio (M‐H, Random, 95% CI)	0.85 [0.64, 1.13]
2 Early fungicidal activity	2	223	Mean Difference (IV, Random, 95% CI)	‐0.02 [‐0.06, 0.02]
3 DAIDS grade 3/4 toxicities	1		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
3.1 Anaemia	1	198	Risk Ratio (M‐H, Random, 95% CI)	0.63 [0.43, 0.91]
3.2 Renal dysfunction	1	198	Risk Ratio (M‐H, Random, 95% CI)	1.0 [0.14, 6.96]
3.3 Neutropenia	1	198	Risk Ratio (M‐H, Random, 95% CI)	4.5 [1.00, 20.30]
3.4 Hypokalaemia	1	198	Risk Ratio (M‐H, Random, 95% CI)	0.65 [0.34, 1.23]