Comparison 9. Two weeks of AmBd + 5FC versus two weeks of AmBd + FLU.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Mortality	4		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 2 weeks	4	538	Risk Ratio (M‐H, Random, 95% CI)	0.80 [0.55, 1.16]
1.2 10 weeks	4	538	Risk Ratio (M‐H, Random, 95% CI)	0.90 [0.69, 1.17]
1.3 6 months	1	199	Risk Ratio (M‐H, Random, 95% CI)	0.75 [0.53, 1.06]
2 Early fungicidal activity	4	474	Mean Difference (IV, Random, 95% CI)	‐0.09 [‐0.14, ‐0.05]
3 DAIDS grade 3/4 toxicities	3		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
3.1 Anaemia	3	507	Risk Ratio (M‐H, Random, 95% CI)	1.17 [0.89, 1.55]
3.2 Renal dysfunction	3	507	Risk Ratio (M‐H, Random, 95% CI)	0.65 [0.31, 1.37]
3.3 Neutropenia	3	507	Risk Ratio (M‐H, Random, 95% CI)	1.10 [0.61, 1.98]
3.4 Hypokalaemia	3	507	Risk Ratio (M‐H, Random, 95% CI)	1.20 [0.63, 2.27]
3.5 ALT abnormality	2	308	Risk Ratio (M‐H, Random, 95% CI)	0.33 [0.07, 1.60]