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. 2018 Jul 25;2018(7):CD005647. doi: 10.1002/14651858.CD005647.pub3

Comparison 11. One week of AmBd + FLU versus two weeks of AmBd + FLU.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Mortality 1   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
1.1 2 weeks 1 225 Risk Ratio (M‐H, Random, 95% CI) 1.48 [0.95, 2.29]
1.2 10 weeks 1 225 Risk Ratio (M‐H, Random, 95% CI) 1.18 [0.88, 1.58]
2 Early fungicidal activity 1 175 Mean Difference (IV, Random, 95% CI) 0.01 [‐0.06, 0.08]
3 DAIDS grade 3/4 toxicities 1   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
3.1 Anaemia 1 225 Risk Ratio (M‐H, Random, 95% CI) 0.88 [0.55, 1.42]
3.2 Renal dysfunction 1 225 Risk Ratio (M‐H, Random, 95% CI) 0.81 [0.38, 1.70]
3.3 Neutropenia 1 225 Risk Ratio (M‐H, Random, 95% CI) 0.72 [0.28, 1.82]
3.4 Hypokalaemia 1 225 Risk Ratio (M‐H, Random, 95% CI) 0.57 [0.20, 1.65]
3.5 ALT abnormality 1 225 Risk Ratio (M‐H, Random, 95% CI) 0.34 [0.07, 1.66]