EUCTR2010‐018592‐16‐DK.

Methods	Randomized controlled study within the ABC cohort (Asthma Begins in Childhood)
Participants	Participants in the ABC cohort study. Resident of Copenhagen, Sjælland, Møn, Lolland, or Falster. Both parents are Danish‐speaking. Parents agree to enrol the child. The child is at least 1 year old and has had 1 of the following asthma symptoms: 5 episodes within 6 mdr (1 episode: 3 consecutive days with lower airway symptoms) or 4 weeks daily lung symptoms or acute severe asthma
Interventions	Intervention: azithromycin (oral suspension, 40 mg/mL) Control: placebo oral suspension, same volume as active drug
Outcomes	Primary endpoint(s) Changes in symptom score from day 1 until termination of each asthmatic episode during the age of 1 to 3 years Duration of each asthmatic episode Secondary endpoint(s): no secondary endpoints
Notes	Study Title: antibiotics as a treatment of repeated asthmatic symptoms in children ‐ a randomised, controlled study within the ABC cohort (Asthma Begins in Childhood) Date of first registration: 04/10/2010; last refreshed: 20/09/2016, with status currently no longer recruiting Registered on EU clinical trial register No contact details available