Borenstein 2003a.

Methods	Randomised trial
Participants	197 hypertensive patients (intervention; 98 control) 2 main offices of one medical practice of general internists and internal medicine sub‐specialists affiliated with a large community hospital USA Year of study: 1996 to 1998
Interventions	The intervention was made up of visits by pharmacist who assessed adherence to antihypertensive drugs, side effects, patient habits in accordance with guidelines as well as education about lifestyle modifications. Also follow‐up visits with physicians for treatment plans. On average there were 8 provider interactions over a 12‐month period.
Outcomes	Systolic blood pressure at 12 months Number achieving blood pressure goals at 12 months
Notes	Funding source: Not specificed. Conflict of interest: Not stated.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Unclear what method of randomisation was used
Allocation concealment (selection bias)	Unclear risk	Unclear if patients or personnel were aware of allocation during recruitment
Blinding of participants and personnel (performance bias) All Outcomes/Outcome 1	Low risk	BP measurement has low risk of performance bias.
Blinding of outcome assessment (detection bias) All Outcomes/Outcome 1	Unclear risk	Unclear regarding method of BP measurement and whether assessor was blind to allocation.
Incomplete outcome data (attrition bias) All outcomes	High risk	99/635 and 98/637 completed. Between group attrition < 10% but overall attrition >80%.
Selective reporting (reporting bias)	Low risk	All outcomes reported
Other bias	Low risk	None identified