Goodyer 1995.

Methods	Randomised trial
Participants	100 patients > 70 years (intervention 50;control 50) Outpatient clinics of the Medicine for Elderly Department at Charing Cross Hospital United Kingdom Year of study: Not stated.
Interventions	Verbal counselling on the correct use of medication + medication calendar and information leaflets Length of intervention: 3 domiciliary visits over a 6‐ to 12‐week period
Outcomes	Compliance (pill count) defined as the % of the number that should have been consumed Patient knowledge Exercise test (distance in 6 minutes and distance until breathless) Clinical assessment Nottingham Health Profile Breathlessness when performing different activities
Notes	Funding source: Not specified Conflict of interest: Not stated
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "patients were randomly allocated to intervention or control groups"
Allocation concealment (selection bias)	Unclear risk	Allocation procedure not described explicitly No information provided
Blinding of participants and personnel (performance bias) All Outcomes/Outcome 1	Unclear risk	Personnel were not blinded. Unclear if this caused bias
Blinding of outcome assessment (detection bias) All Outcomes/Outcome 1	Low risk	Quote: "clinical assessments [were] carried out by a physicians blinded to group allocation."
Incomplete outcome data (attrition bias) All outcomes	Low risk	Between group attrition < 10%.
Selective reporting (reporting bias)	Low risk	Main results reported
Other bias	Low risk	None