Hunt 2008.
Methods | Randomised trial | |
Participants | 463 hypertensive patients (intervention 230; control 233). 9 community‐based primary care clinics from primary care research network Oregon, USA Year of study: Not stated. |
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Interventions | Intervention comprised physician‐pharmacist collaboration following hypertension management guidelines. Pharmacists reviewed medication, lifestyle habits, assessed vital signs and reactions, provided education, identification of barriers to adherence and provided a regimen. Average of 7.2 total visits between pharmacists and physicians | |
Outcomes | Systolic and diastolic blood pressure (BP) at 12 months SF‐36 (physical functioning) at 12 months BP in range |
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Notes | Funding source: Boehringer Ingelheim funded the cost of the educational mailings and the conduction of the study. Conflict of interest: All data collection, analysis, and reporting were conducted by the study investigators and the Providence research staff. The investigators report no other conflict of interest. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Using a computer‐generated random sequence |
Allocation concealment (selection bias) | Low risk | Using a computer‐generated random sequence |
Blinding of participants and personnel (performance bias) All Outcomes/Outcome 1 | High risk | Participant blinding was not possible. Knowledge of allocation may have influenced behaviour. |
Blinding of outcome assessment (detection bias) All Outcomes/Outcome 1 | Low risk | Blood pressure was assessed by registered nurses blinded to participants’ randomisation allocation |
Incomplete outcome data (attrition bias) All outcomes | High risk | Between group attrition < 10% but overall attrition rate >40% |
Selective reporting (reporting bias) | Low risk | All outcomes reported |
Other bias | Low risk | None identified |