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. 2018 Sep 4;2018(9):CD013102. doi: 10.1002/14651858.CD013102

Hunt 2008.

Methods Randomised trial
Participants 463 hypertensive patients (intervention 230; control 233).
9 community‐based primary care clinics from primary care research network
Oregon, USA
Year of study: Not stated.
Interventions Intervention comprised physician‐pharmacist collaboration following hypertension management guidelines. Pharmacists reviewed medication, lifestyle habits, assessed vital signs and reactions, provided education, identification of barriers to adherence and provided a regimen. Average of 7.2 total visits between pharmacists and physicians
Outcomes Systolic and diastolic blood pressure (BP) at 12 months
SF‐36 (physical functioning) at 12 months
 BP in range
Notes Funding source: Boehringer Ingelheim funded the cost of the educational mailings and the conduction of the study.
Conflict of interest: All data collection, analysis, and reporting were conducted by the study investigators and the Providence research staff. The investigators report no other conflict of interest.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Using a computer‐generated random sequence
Allocation concealment (selection bias) Low risk Using a computer‐generated random sequence
Blinding of participants and personnel (performance bias) 
 All Outcomes/Outcome 1 High risk Participant blinding was not possible. Knowledge of allocation may have influenced behaviour.
Blinding of outcome assessment (detection bias) 
 All Outcomes/Outcome 1 Low risk Blood pressure was assessed by registered nurses blinded to participants’ randomisation allocation
Incomplete outcome data (attrition bias) 
 All outcomes High risk Between group attrition < 10% but overall attrition rate >40%
Selective reporting (reporting bias) Low risk All outcomes reported
Other bias Low risk None identified