Lenaghan 2007.

Methods	Randomised trial
Participants	136 elderly patients (intervention 69; control 67). 1 community pharmacist and patients from 1 general practice Norfolk, England Year of study: Not stated.
Interventions	2 home visits by a community pharmacist discussing drug interactions, education of medicines, removal of out‐of‐date drugs and assessment of need for adherence aid. Visits were arranged to include the carer of the elderly patient. Pharmacists discussed any issues with the general practitioner for possible changes to medication prescription.
Outcomes	Euroqol (EQ)‐5D Hospital admissions All‐cause mortality
Notes	Funding source: The main author’s post was funded by NHS Executive Eastern Region research funding. Conflict of interest: The medication review intervention was funded by Holt Medical Practicewho hosted the research.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "Randomisation was carried out by a third party, and was stratified by whether the patient lived alone."
Allocation concealment (selection bias)	Unclear risk	Unclear if the person enrolling the participant was aware of allocation
Blinding of participants and personnel (performance bias) All Outcomes/Outcome 1	High risk	Knowing they were in the intervention group may have resulted in behaviour change.
Blinding of outcome assessment (detection bias) All Outcomes/Outcome 1	Low risk	Hospital readmissions, deaths etc. not likely to be influenced
Incomplete outcome data (attrition bias) All outcomes	High risk	Between group attrition < 10% however overall completion rate <80%.
Selective reporting (reporting bias)	Low risk	All outcomes reported
Other bias	Low risk	None identified