Tang 2014.
| Methods | Randomised trial | |
| Participants | 124 participants with epilepsy (intervention 59: control 65) Patients with epilepsy who were treated at the outpatient clinic of Neurology Huashan Hospital, University of Fudan, Shanghai, China Year of study: Not stated. |
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| Interventions | Education and behavioural intervention Intervention patients were educated by a pharmacist according to the guidelines of the American Society of Health‐System Pharmacists about pharmacist‐conducted patient education and counselling. Patients received monthly calls from the pharmacist and were instructed about their medications and asked to adhere to their anti‐epileptic medication. There was also a behavioural intervention based on cue‐dose training therapy. The medication schedule used in this programme was presented in the form of a table that illustrated the daily medication therapy of patients with pictures of anti‐epileptic medication, and it provided patients with cues to take their medications. Frequency: Monthly phone calls, initial education session, persistent cues Duration: 6 months |
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| Outcomes | Seizure control (50% reduction from baseline), Quality of life | |
| Notes | Funding source: Not specified Conflict of interest: None stated |
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| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Low risk | A list of 300 random numbers between 0 and 9 was generated using a statistical package. The patients were numbered according to the order in which they were recruited. Patients who had received an even randomly‐generated number were assigned to group I, and patients who received odd numbers were assigned to group II. |
| Allocation concealment (selection bias) | Unclear risk | Not stated |
| Blinding of participants and personnel (performance bias) All Outcomes/Outcome 1 | High risk | Unblinded study with substantial potential bias |
| Blinding of outcome assessment (detection bias) All Outcomes/Outcome 1 | Low risk | Seizure change: low risk |
| Incomplete outcome data (attrition bias) All outcomes | Low risk | Between group attrition < 10%. |
| Selective reporting (reporting bias) | Low risk | All reported |
| Other bias | Low risk | None |