Table 1.
Lung metal deposition in A/J mice after stainless steel welding fume inhalation for 4 h at a target concentration of 40 mg/m3
| Exposure | Cr (μg/lung) | Cu (μg/lung) | Fe (μg/lung) | Mn (μg/lung) | Ni (μg/lung) |
|---|---|---|---|---|---|
| Air | 0.02 ± 0.01 | 0.22 ± 0.03 | 8.97 ± 0.36 | 0.02 ± 0.00 | 0.01 ± 0.00 |
| GMA-SS | 1.65 ± 0.05 | 0.32 ± 0.01 | 15.12 ± 0.39 | 1.48 ± 0.04 | 0.82 ± 0.02 |
Freeze-dried whole-lung tissue was analyzed for aluminum (Al), chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), nickel (Ni), titanium (Ti), and zinc (Zn) by Inductively Coupled Plasma-Atomic Emission Spectroscopy. Samples were prepared according to draft NIOSH Analytical Method 8200 for bulk tissue samples. Trace amounts of Al, Ti, and Zn were found. In cases in which no result was measured, the limit of quantification (LOQ) was used in calculating the average deposition. Values are mean ± standard error of the mean (n = 10 air; n = 25 GMA-SS); GMA-SS—gas metal arc-stainless steel welding fume