Date	Event	Description
17 July 2018	New search has been performed	Placebo‐controlled studies of carotenes or retinoids other than vitamin A are now also eligible for inclusion. A new search with extended search terms of the Cystic Fibrosis and Genetic Disorders Review Group's Cystic Fibrosis Trials Register identified 13 references to five studies. An additional search of trials registries identified one ongoing study. One study with seven references has been included in this review (Rust 1998) and the remaining studies have been excluded (Cobanoglu 2002; Garić 2015; Homnick 1995; NCT01859390; Wood 2003). The format of the plain language summary has been updated in line with current guidance and a summary of findings table has been added.
17 July 2018	New citation required and conclusions have changed	While our original conclusions on vitamin A supplementation have not changed, new conclusions on the use of carotenes or retinoids supplementation have been drawn. The author team has been expanded with two new authors, Jorrit de Vries and Julie Marchant.
6 May 2014	New search has been performed	A search of the Group's Cystic Fibrosis Trials Register did not identify any new studies potentially eligible for inclusion in this review.
6 May 2014	New citation required but conclusions have not changed	No new studies were included so the conclusions of the review have not changed.
7 June 2012	New citation required but conclusions have not changed	No new studies were included so the conclusions of the review have not changed.
7 June 2012	New search has been performed	A search of the Group's Cystic Fibrosis Trials Register did not identify any new references potentially eligible for inclusion in this review.
1 December 2009	New search has been performed	A search of the Group's Cystic Fibrosis Trials Register identified a single reference which was excluded (Wood 2003).
12 August 2009	Amended	Contact details updated.
10 April 2008	New search has been performed	A search of the Group's Cystic Fibrosis Trials Register did not identify any trials which might be eligible for inclusion in this review.
10 April 2008	Amended	Converted to new review format.