Comparison 27. Enteral plus parenteral nutrition versus other nutrition regimens.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Nosocomial pneumonia	1	120	Risk Ratio (M‐H, Fixed, 95% CI)	0.79 [0.44, 1.40]
1.1 Enteral plus parenteral nutrition vs enteral nutrition	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	0.6 [0.29, 1.25]
1.2 Enteral plus parenteral nutrition vs parenteral nutrition	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	1.25 [0.47, 3.33]
2 All‐cause mortality in hospital	1	120	Odds Ratio (M‐H, Fixed, 95% CI)	0.20 [0.06, 0.60]
2.1 Enteral plus parenteral nutrition vs enteral nutrition	1	60	Odds Ratio (M‐H, Fixed, 95% CI)	0.26 [0.05, 1.30]
2.2 Enteral plus parenteral nutrition vs parenteral nutrition	1	60	Odds Ratio (M‐H, Fixed, 95% CI)	0.15 [0.03, 0.74]
3 Duration of ICU stay	1	120	Mean Difference (IV, Fixed, 95% CI)	‐5.98 [‐8.81, ‐3.16]
3.1 Enteral plus parenteral nutrition vs enteral nutrition	1	60	Mean Difference (IV, Fixed, 95% CI)	‐3.81 [‐7.59, ‐0.03]
3.2 Enteral plus parenteral nutrition vs parenteral nutrition	1	60	Mean Difference (IV, Fixed, 95% CI)	‐8.72 [‐12.97, ‐4.47]
4 Duration of intubation	1	120	Mean Difference (IV, Fixed, 95% CI)	‐7.37 [‐9.29, ‐5.45]
4.1 Enteral plus parenteral nutrition vs enteral nutrition	1	60	Mean Difference (IV, Fixed, 95% CI)	‐4.17 [‐6.96, ‐1.38]
4.2 Enteral plus parenteral nutrition vs parenteral nutrition	1	60	Mean Difference (IV, Fixed, 95% CI)	‐10.24 [‐12.88, ‐7.60]
5 Adverse events ‐ stress ulcer	1	120	Risk Ratio (M‐H, Fixed, 95% CI)	0.69 [0.36, 1.33]
5.1 Enteral plus parenteral nutrition vs enteral nutrition	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	1.14 [0.38, 3.45]
5.2 Enteral plus parenteral nutrition vs parenteral nutrition	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	0.53 [0.23, 1.20]
6 Adverse events ‐ diarrhoea	1	120	Odds Ratio (M‐H, Fixed, 95% CI)	0.42 [0.17, 1.02]
6.1 Enteral plus parenteral nutrition vs enteral nutrition	1	60	Odds Ratio (M‐H, Fixed, 95% CI)	0.17 [0.05, 0.59]
6.2 Enteral plus parenteral nutrition vs parenteral nutrition	1	60	Odds Ratio (M‐H, Fixed, 95% CI)	1.42 [0.35, 5.73]
7 Adverse events ‐ pyaemia	1	120	Odds Ratio (M‐H, Fixed, 95% CI)	0.88 [0.37, 2.09]
7.1 Enteral plus parenteral nutrition vs enteral nutrition	1	60	Odds Ratio (M‐H, Fixed, 95% CI)	4.11 [0.87, 19.41]
7.2 Enteral plus parenteral nutrition vs parenteral nutrition	1	60	Odds Ratio (M‐H, Fixed, 95% CI)	0.37 [0.11, 1.21]
8 Adverse events ‐ intracranial infection	1	120	Odds Ratio (M‐H, Fixed, 95% CI)	0.43 [0.15, 1.25]
8.1 Enteral plus parenteral nutrition vs enteral nutrition	1	60	Odds Ratio (M‐H, Fixed, 95% CI)	0.83 [0.19, 3.63]
8.2 Enteral plus parenteral nutrition vs parenteral nutrition	1	60	Odds Ratio (M‐H, Fixed, 95% CI)	0.23 [0.05, 1.15]
9 Adverse events ‐ hypoproteinaemia	1	120	Odds Ratio (M‐H, Fixed, 95% CI)	0.11 [0.04, 0.27]
9.1 Enteral plus parenteral nutrition vs enteral nutrition	1	60	Odds Ratio (M‐H, Fixed, 95% CI)	0.20 [0.06, 0.72]
9.2 Enteral plus parenteral nutrition vs parenteral nutrition	1	60	Odds Ratio (M‐H, Fixed, 95% CI)	0.04 [0.01, 0.19]